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Medical News & Perspectives
March 14, 2017

US Uterus Transplant Trials Under Way

JAMA. 2017;317(10):1005-1007. doi:10.1001/jama.2016.20735

Mats Brännström, MD, PhD, was beyond skeptical when a patient undergoing a hysterectomy for cervical cancer in 1998 asked him for a uterus transplant to restore her fertility.

“I thought she was crazy,” said the professor of obstetrics and gynecology at the University of Gothenburg in Sweden.

But the request set off a more than decade-long effort by Brännström, a fertility researcher and gynecologic surgeon, and his colleagues to determine whether transplanting a uterus was feasible. Meanwhile, groups in Saudi Arabia and Turkey sought to answer the same question. Even though they performed the first 2 human transplants, neither resulted in a successful pregnancy.