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March 27, 1943


JAMA. 1943;121(13):1109. doi:10.1001/jama.1943.02840130123023

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To the Editor:—  The wide range of safe deviation of body temperature below, normal was demonstrated by Temple Fay several years ago and has been demonstrated since by many others in the treatment of carcinomatosis. I am not familiar with any previous knowledge of general human refrigeration."Deliberate maintenance of temperatures around 90 F., rectal, in cases of severe trauma" and "what refrigeration will do for burns" should be matters of great interest. There is ample experimental support for the belief that there is an optimum "subnormal" temperature for shock states at which the metabolism is at its lowest level. Deviation from this optimum "subnormal" level, either warming or cooling, lessens the chances of recovery (Elman, Robert; Cox, W. M., Jr.; Lischer, Carl, and Mueller, A. J.: Mortality in Severe Experimental Burns as Affected by Environmental Temperature, Proc. Soc. Exper. Biol. & Med.51:350 [Dec.] 1942).Carefully controlled assistance

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