A man with a 3-year history of chronic obstructive pulmonary disease presented with increasing dyspnea on exertion, requiring increasing flow rates of oxygen. He was a former smoker with a 50–pack-year history. He had been diagnosed with stage I low-grade prostate cancer several years previously.
Lung examination showed no wheezing. Cardiac examination showed a prominent pulmonary component (P2) of the second heart sound. Noncontrast computed tomography of the chest was unremarkable.
Medarov B, Chaudhry H, Myint T. Increasing Hypoxemia and Dyspnea in Mild Chronic Obstructive Pulmonary Disease. JAMA. 2017;317(10):1072–1073. doi:10.1001/jama.2016.20179
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