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To the Editor:—
In the March 6 issue of The Journal, page 719, in an article by Carl H. Greene entitled "Physiologic Considerations in the Treatment of Portal Cirrhosis," the statement is made that "the patient with cirrhosis frequently shows a reduction in the prothrombin time of the blood which, if pronounced, will cause a tendency to hemorrhage."It seems apparent that the author meant to express himself in terms of a reduction of the prothrombin level rather than in terms of a reduction of the prothrombin time. It is the reduction of the prothrombin level of the blood which will cause a tendency to hemorrhage. Such a condition, however, is associated with a prolongation of the prothrombin time and not with a reduction of the prothrombin time as mentioned in the author's paper.Such terminology may seem confusing to the casual reader. For the sake of clarity it should
Saphir W. PORTAL CIRRHOSIS. JAMA. 1943;121(16):1304. doi:10.1001/jama.1943.02840160054021
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