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April 24, 1943

ACNE CONGLOBATA AND PERIANAL PYODERMA (HIDRADENITIS SUPPURATIVA): PROMPT RESPONSE TO LOW FAT DIET AND THYROXINE THERAPY

Author Affiliations

Kansas City, Mo.

JAMA. 1943;121(17):1344-1347. doi:10.1001/jama.1943.62840170003008b
Abstract

Acne conglobata is a chronic inflammatory disease of the skin which is characterized1 "by the presence of the constituents of acne vulgaris, such as comedones, papules and pustules, and in addition large, elevated, fluctuating plaques which are dusky blue and frequently form cutaneous or subcutaneous abscesses and oil cysts, which may perforate and form discharging sinuses, healing very slowly and often leaving keloidal or so-called bridge scars (brückennarben) of Lang. The lesions closely resemble tuberculodermas of the colliquative type (scrofuloderma)." Ormsby2 credited Reitman with the first description of the disease, in 1908, occurring in 4 men who had "innumerable comedones, many double comedones and comedo scars together with follicular and perifollicular inflammatory infiltrations, often confluent, some of which had softened and were open.... Pautrier described a case in which torpid abscesses, keloid fibrous bridges and other hyperplastic fibrous formations occurred in the early stages in the usual acne

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