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April 24, 1943


JAMA. 1943;121(17):1353. doi:10.1001/jama.1943.02840170037012

A new virus papilloma is described by Parsons and Kidd,1 a noncancerous papillomatosis of the oral lining of domestic rabbits. The growths are situated mainly on the under side of the tongue. Parsons and Kidd have extracted a filtrable virus from these growths which reproduces the disease in the oral mucosa of rabbits. As yet there has been no effect in other rabbit tissues or in the oral mucosa of other animals. This form of virus papilloma, of which there now is a considerable number, does not show any tendency to become cancerous. Its natural transmission appears to be "by a direct handing along in the family."

Further studies of feline agranulocytosis by Syverton and Lawrence and their associates2 show that the specific virus of this disease is not related to various other pathogenic viruses, human and animal, and that it produces a specific immunity. The disease is