The term leiomyosarcoma implies sarcomatous changes in a tumor composed chiefly of relatively histologically mature but physiologically immature unstriped muscle cells. The type of tumor under consideration is also referred to by various pathologists as leiomyoblastoma, myosarcoma, myoma malignum and highly cellular myoma. The several names used to designate the same neoplasm evidently depend to a large extent on the individual pathologist's interpretation of the cellular picture, and his conception of its actual or potential malignancy. Corscaden1 has recently said: "The development of sarcoma in a myoma is to me an academic and not a clinical problem. Despite the report of bizarre microscopic pictures, called sarcoma by many investigators of myomatous tissue, the autopsy rooms still remain as empty of women dead of sarcoma of the uterus as they did in the years before hysterectomy was so universally performed." Most physicians of experience will admit that primary sarcoma of
DANNREUTHER WT. LEIOMYOSARCOMA OF THE UTERUS: IDENTITY, MALIGNANCY AND TREATMENT. JAMA. 1928;91(20):1532–1537. doi:10.1001/jama.1928.02700200030011
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