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May 15, 1943


Author Affiliations

Bethesda, Md. Principal Pharmacologist, U. S. Public Health Service.

JAMA. 1943;122(3):193. doi:10.1001/jama.1943.02840200049021

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To the Editor:—  An editorial comment (The Journal, April 3, p. 1157) on the "Therapy of Severe Burns" calls attention to the report of Elman, Cox, Lischer and Mueller (Proc. Soc. Exper. Biol. & Med.51:350 [Dec.] 1942). These authors, working with experimental burns in rats, demonstrated that the acute mortality was greatly elevated in animals kept at environmental temperatures of 32, 55 and 99 F. as compared with groups of rats kept at 75 F.May I call your attention to the fact that I have reported similar results in mice in an article entitled "Experimental Chemotherapy of Burns and Shock: I. Methods. II. Effects of Local Therapy on Mortality from Shock" (Pub. Health Rep.57:1923 [Dec. 18] 1942), which appeared simultaneously with the publication cited. Mention should also be made of the recent article of Wakim and Gatch, "Effects of Temperature on Shock," which appeared in

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