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May 22, 1943

Current Comment

JAMA. 1943;122(4):234. doi:10.1001/jama.1943.02840210026011

EPIDEMIOLOGY OF RHEUMATIC FEVER  During the past ten years great activity has taken place in research on rheumatic fever. As pointed out by Paul,1 appreciable strides have been made in understanding the epidemiology of rheumatic fever, owing in large part to the notable contributions of Hedley on rheumatic heart disease in Philadelphia hospitals. The appreciation of the pathogenesis of this disease has taken a new turn with the recognition of its close relationship to hemolytic streptococcus infections—a development based largely on the work of Coburn. Observations along these lines have wrought a profound change in present conceptions regarding the nature of rheumatic fever. The recent publication of a new edition of a book on the epidemiology of rheumatic fever, the first edition of which was published in 1931, constitutes a welcome summary at this time. It reviews the present status of the associations between rheumatic fever and acute hemolytic