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May 29, 1943

Pancreatic Function and Pancreatic Disease Studied by Means of Secretin

JAMA. 1943;122(5):346. doi:10.1001/jama.1943.02840220078038

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In his foreword to this monograph, Dr. Pratt summarizes its import by saying that the work reported by Lagerlöf has lifted pancreatic analysis to the level gastric analysis has occupied for many years. Almost half of the volume is concerned with a historical survey of research on the physiology of the pancreas and a description and critique of methods for the analysis of the pancreatic enzymes. There follows a relatively brief section on the secretin test as used by the author and his collaborators, and the results obtained with it on normal individuals and on patients suffering from pancreatic disease. The remaining approximately one third of the book is devoted to summarized case histories of 37 patients with proved diseases of the pancreas and of 26 patients with suspected pancreatic disease. An appendix contains tabular data illustrating the author's experimental work and summarizing control tests on normal subjects. A bibliography

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