Iodized poppy seed oil has been injected intraspinally in thousands of instances for the localization of intraspinal lesions. Apart from obvious disadvantages in some medicolegal situations and mild transitory symptoms for a few hours to a few days immediately after its injection in a small percentage of the cases, its use has been remarkably free from any untoward results. In our experience, the intraspinal use of iodized oil has been so innocuous that one of us (P. C. B.) has repeatedly expressed the opinion that its use was not associated with any permanent undesirable effects and that in those few instances in the literature in which the development of symptoms was attributed to the use of iodized oil the case against the oil had by no means been established. Furthermore, the study made by Marcovich, Walker and Jessico 1 at the University of Chicago while the Division of Neurology and
Bucy PC, Speigel IJ. AN UNUSUAL COMPLICATION OF THE INTRASPINAL USE OF IODIZED OIL. JAMA. 1943;122(6):367–369. doi:10.1001/jama.1943.72840230001006
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