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The subject matter is divided into five main parts: introductory—anatomic and physiologic foundation, adjustment reactions involving primarily the respiratory and circulatory system, autonomic-endocrine integration, autonomic-somatic integration and results and applications, physiologic and clinical. The discussion is based largely on work done in the author's own laboratory during the past six years. His chief interest is in the various organ reactions leading to a net result in the whole organism rather than in the physical and chemical basis of activity in any single organ. He tries to show that the autonomic nervous system is not only an efferent system carrying impulses from the somatic system to various visceral organs but also an afferent system whose impulses significantly alter the excitability of the somatic system. His studies also lead him to a reconsideration of the validity of the principle of reciprocal innervation as applied to the sympatheticoadrenal and the vagoinsulin systems. An
Autonomic Regulations: Their Significance for Physiology, Psychology and Neuropsychiatry. JAMA. 1943;122(6):408. doi:10.1001/jama.1943.02840230060030
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