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The basis of this treatise is the experience gained with 100 cases of acute mediastinitis. These are divided into four groups: (1) mediastinitis secondary to esophageal trauma (of special importance is the fact that mediastinitis may result from instrumentation of the esophagus with nonpenetrating trauma of this passage), (2) those secondary to upper respiratory infections, (3) those secondary to pulmonary or pleural infections and (4) those of miscellaneous causation. The case presentations are rendered quite vivid by the publication of roentgenograms and accompanying line diagrams to emphasize the important features. There is a well written section on the surgical anatomy of the mediastinum, and the pathology and bacteriology of mediastinitis. The general clinical aspects are discussed in a separate section apart from the detailed case reports, with emphasis placed on roentgenologic diagnosis. Treatment is discussed in detail in the final section. The importance of correct surgical management is emphasized by
Acute Infections of the Mediastinum. JAMA. 1943;122(6):408. doi:10.1001/jama.1943.02840230060031
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