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June 12, 1943

Lupus eritematoso (estudio clínico sobre 156 observaciones)

JAMA. 1943;122(7):474. doi:10.1001/jama.1943.02840240064035

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The author summarizes his extensive studies in twenty-nine conclusions, some of which follow. The incidence of the disease is 0.78 per cent of the total of dermatoses studied. Its relation to genuine skin tuberculosis is at the rate of 3 to 1. Cases in females are twice as frequent as in males, the highest incidence being between 20 and 30 years. Epithelioma as a complication was observed in only 2 cases. Sixty per cent showed radiologic signs of tuberculosis and 80 per cent responded to the intradermoreaction with tuberculin. Tuberculosis is not the only cause, for the disease is systemic and the result of several factors. Treatment with chaulmoogra oil and bismuth salts gives satisfactory results. Three hundred and eighty-four references and numerous illustrations are appended.

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