[Skip to Content]
[Skip to Content Landing]
Article
June 26, 1943

PROPHYLACTIC USE OF SULFAGUANIDINE

JAMA. 1943;122(9):588-591. doi:10.1001/jama.1943.02840260016004
Abstract

On Oct. 24, 1941 a case of diarrhea with fever developed at the Devereux Gateway School, which is one unit of the schools operated by the Devereux Foundation, Devon, Pa.1 This unit is operated for the care and training of children from 3 to 8 years of age, all of whom are mentally defective to some extent. On the following day the second child became ill in the same manner, and from then on, in spite of the usual treatment used for the control of diarrhea in childhood, we were faced with a rapidly developing epidemic in the building with all cases running virtually the same course of illness.

Cultures of the stools of all children were made, and the Bryn Mawr Hospital Laboratory2 isolated from 4 active cases organisms identified as the Sonne type of dysentery bacillus. Details of the symptoms, together with the laboratory findings, gave

×