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Article
July 3, 1943

PYURIA OF THE NEWBORN TREATED WITH SULFATHIAZOLE: A REPORT OF THREE CASES ILLUSTRATING DIFFERENT ASPECTS OF THE SYNDROME

Author Affiliations

NEW YORK

From the Pediatric Service of the Mount Sinai Hospital.

JAMA. 1943;122(10):656-658. doi:10.1001/jama.1943.02840270014005
Abstract

During the neonatal period changes take place very rapidly in the anatomy and physiology of the child. These changes are often reflected in those disease pictures peculiar to this period of life. Examples of such conditions are tetany of the newborn, paroxysmal tachycardia, pyloric stenosis and the condition we are describing in this communication, namely pyuria of the newborn. In all these conditions the change from fetal to extrauterine existence, with the sudden alteration in physiologic processes this entails, may easily account for disturbances in the smooth functioning of the various organs. It is our purpose in this communication to reemphasize this observation and to report 3 cases of pyuria of the newborn treated with sulfathiazole.

The newborn child's urine may contain casts and cellular elements in the absence of disease.1 These usually clear with the ingestion of large amounts of fluid.2 However, there are reports in the

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