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May 2, 2017

Managing Conflicts of Interest in Industry-Sponsored Clinical ResearchMore Physician Engagement Is Required

Author Affiliations
  • 1Johnson & Johnson, New Brunswick, New Jersey
  • 2Emory University, Atlanta Georgia
JAMA. 2017;317(17):1751-1752. doi:10.1001/jama.2017.4160

Companies engaged in health care research and development share, with health professionals, academic health centers, patient advocacy organizations, and other medical and health-related institutions, the mission to improve human health. Companies play indispensable roles in advancing almost all aspects of this mission, including sponsoring clinical research and generating clinical data that serve as the basis for drug and device approvals, guidelines, and prescribing information. Clinical research must be conducted with the utmost scientific rigor, integrity, and compassion. It has long been recognized that the dual obligations companies have to both patients and shareholders create real and perceived conflicts of interest (COIs). If not properly managed, COIs can undermine physician and patient trust in industry-supported development of drugs and devices.1,2

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