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Comment & Response
May 16, 2017

Intubation During In-Hospital Cardiac Arrest—Reply

Author Affiliations
  • 1Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark
  • 2Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
JAMA. 2017;317(19):2019-2020. doi:10.1001/jama.2017.4427

In Reply Dr Wilt and Ms Lee question the validity of our results due to between-group differences in baseline characteristics before propensity matching, specifically mentioning differences in noninvasive ventilation and the initial rhythm. As noted in Table 2 in the article, these characteristics were well matched in the propensity score–matched cohort. Therefore, these variables cannot confound the adjusted results. Furthermore, in our subgroup analysis according to initial rhythm, intubation was associated with poor outcomes in both those with initial shockable and nonshockable rhythms. As noted in the article, there might be unmeasured confounders we were unable to adjust for.