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August 8, 1931


JAMA. 1931;97(6):393-394. doi:10.1001/jama.1931.02730060031013

Filariasis remained a puzzling problem for many years until the nature of the parasites involved, their life histories, and the modes of transmission to man became better known. Filariated persons are found in large numbers in certain parts of the world, particularly in tropical regions. The filarial organisms occur in the body in both adult and larval forms, the latter being designated microfilariae. They are transmitted by insect vectors. Closely related to the familiar filariae are organisms belonging to the genus Onchocerca. They lead to the development of fibrous tumors, usually under the skin, in which the parasites are embedded. Some of the tumors are of long duration in man and, in some adults, are said to have been present since childhood. According to Chandler,1 in some districts of Congo where Filaria bancrofti is said not to occur, practically all cases of elephantiasis are accompanied by infection with Onchocerca