[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.238.190.122. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
July 24, 1943

MULTIPLE SPONTANEOUS IDIOPATHIC SYMMETRICAL FRACTURES: MILKMAN'S SYNDROME

Author Affiliations

PHILADELPHIA

From the Medical Service of Dr. Abraham Trasoff and the Department of Radiology, Mount Sinai Hospital.

JAMA. 1943;122(13):865-870. doi:10.1001/jama.1943.02840300025007
Abstract

In 1930 and in 1934 Milkman1 reported a case exhibiting a skeletal osteopathy which he considered unique and which he named "multiple spontaneous idiopathic symmetrical fractures." In the succeeding twelve years we were able to find references to only 3 similar cases2 in the English literature and to 15 cases in the foreign medical literature. Our purpose in this report is to review briefly the literature and to add a twentieth case.

This syndrome is characterized by pain, disturbances of gait and the radiologic appearance of multiple transparent bands or zones often symmetrically located in various portions of the skeleton, usually interpreted as representing fractures. Locomotion eventually becomes so impeded as to render the patient bedfast.

REPORT OF CASE 

History.—  Mrs. H. S., aged 34, a native American housewife, was admitted to Mount Sinai Hospital on July 16, 1942 complaining of weakness, painful lower extremities and inability to

×