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July 24, 1943


Author Affiliations

A. U. S., Army Medical School, Washington, D. C.

JAMA. 1943;122(13):891. doi:10.1001/jama.1943.02840300051019

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To the Editor:—  Since reading your editorial of June 5 I have received from Geneva the report of Yves M. Biraud on "The Present Menace of Typhus Fever in Europe and the Means of Combating It." One fully realizes the great difficulty in summarizing this work in a short article or editorial. It, however, would seem advisable to comment on one statement of Dr. Biraud which you quote in your editorial to the effect that "As regards live vaccines the new method of Blanc (biliated flea virus) and that of Laigret-Durand (mouse brain) are the only ones that can be considered for the preparation of vaccine intended for Europeans...."Biraud gives much reported evidence of the value and earlier use of the Blanc vaccine, which consists of a dried murine virus in feces of infected fleas to which ox bile is added before inoculation. Among these, he states, "mention should

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