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To the Editor:—
I read with interest the report of Dr. Howard L. Alt on "Red Cell Transfusions in the Treatment of Anemia" (The Journal, June 12, p. 417). I fully agree with the author regarding the usefulness of red cell transfusions but would like to point out the desirability of utilizing red cells in the form of concentrated suspensions rather than suspensions diluted with isotonic solution of sodium chloride. After a considerable trial we abandoned the addition of saline solution following aspiration of plasma both on account of technical disadvantages as well as because the addition of isotonic solution of sodium chloride to the red cells which have been stored in citrate-saline solution results in increased erythrocytic fragility and often detectable hemolysis. But we add, preferably at the time of collection of blood, 25 cc. of a 50 per cent dextrose solution for a better preservation of red cells.
Blum LL. RED CELL TRANSFUSIONS. JAMA. 1943;122(13):892. doi:10.1001/jama.1943.02840300052023
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