There has recently been called to my attention a case of erythroblastosis fetalis which occurred in 1 infant of twins, while the other twin is perfectly normal. In view of the recent interest in the blood factor Rh as the etiologic agent of erythroblastosis, I feel that this case is of sufficient importance to warrant publication. Complete blood Rh studies have been carried out in this case and they add further support to the thesis that erythroblastosis is the result of isoimmunization of an Rh negative mother by an Rh positive fetus. Considerable evidence1 has been brought forth to prove the truth of this statement.
In a recent publication2 it was suggested that the term "hemolytic disease of the newborn" be used rather than "erythroblastosis fetalis," since the erythroblastosis seen in the infant is merely one of the results of the underlying cause, which is hemolysis of the
Kariher DH. ERYTHROBLASTOSIS FETALIS (HEMOLYTIC DISEASE OF THE NEWBORN) OCCURRING IN ONE OF TWINS. JAMA. 1943;122(14):943–944. doi:10.1001/jama.1943.72840310001009
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