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During the last thirty-five years clinical pathology has undergone marvelous development. It is now a recognized specialty in medicine with some thousands of physicians who devote themselves exclusively to its practice. Each year new technics are developed which throw still further burdens on the laboratory as the handmaiden of medical skill. An especially new phase is the use of the laboratory as a guide to therapy as occurs in the administration of the sulfonamides or vitamin K. The isolation of viruses, the classifications of Rickettsia, the determination of blood groups and the use of physical methods such as photelometric technics are further examples of the great progress in this field. Moreover, new technics are now submitted promptly to comparative studies and officially evaluated, as, for instance, the multiple serodiagnostic methods used in syphilis. All these technics are described in this work. The present edition is, moreover, enriched with seventy-two new
Clinical Diagnosis by Laboratory Methods: A Working Manual of Clinical Pathology. JAMA. 1943;122(14):980. doi:10.1001/jama.1943.02840310072037
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