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June 6, 2017

Unfolding the Clinical Potential of DNA and Protein Origami

JAMA. 2017;317(21):2154-2155. doi:10.1001/jama.2017.6288

Imagine being able to use nanoscale robots to precisely deliver drugs to tumors or even control when these robots release their payloads with your mind. Researchers are exploring such possibilities by using DNA and protein as building materials to create completely new structures for biomedical applications, among others.

The science is based on the knowledge that within the body, components are continually assembling themselves to grow, adapt, heal, and reproduce. At the most fundamental levels, such self-assembly forms DNA and protein molecules into precise patterns and shapes. Harnessing this potential has wide-ranging implications for preserving health and combating disease.