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Global Health
June 20, 2017

Cholera Vaccine Safe During Pregnancy

JAMA. 2017;317(23):2362. doi:10.1001/jama.2017.7312

Women in Malawi who received a cholera vaccine during pregnancy did not have a higher risk of pregnancy loss or neonatal mortality, according to an observational cohort study carried out by researchers from the United States and Malawi.

Cholera can cause serious complications in pregnant women and their fetuses if the disease is not treated promptly. Shanchol is 1 of 2 oral inactivated cholera vaccines recommended by the WHO to reduce the risk of cholera and is the most common cholera vaccine used in response to outbreaks in low-income countries. However, pregnant women are usually excluded from cholera vaccination campaigns because of a lack of safety data.

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