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August 15, 1931


JAMA. 1931;97(7):465-466. doi:10.1001/jama.1931.02730070031014

Water has long been recognized as an indispensable factor in the normally functioning organism. To be sure, the required quantities vary widely from the relatively large volumes consumed by a lactating mammal to the minute quantities which satisfy certain larvae and which are provided by the so-called metabolic water arising from the combustion of hydrogen. Recent studies of Jackson and Smith1 have emphasized again the fundamental part played by water in animal economy. These investigators fed to young rats a ration that was complete in every way except that the quantity of water was limited. The experiment extended for periods of from 136 to 226 days and included the portion of the life cycle of the rat during which most rapid growth ordinarily takes place. In these studies the deprivation of water caused an absolute cessation of growth, the body weight being maintained at a markedly uniform level throughout