From Jan. 1, 1943 to April 30, 1943 more than 1,300 cases of meningococcic meningitis occurred among military personnel in the Fourth Service Command. During this period the attack rate for the disease varied widely from post to post. In some installations only sporadic cases were found; in others the number of cases reached epidemic proportions. Generally speaking, however, the disease was more prevalent in stations where large numbers of recently inducted men were assembled for training purposes.
The customary control measures employed during outbreaks of meningococcic meningitis include quarantine, prevention of overcrowding, protection from fatigue and exposure, and the prompt hospitalization or isolation of all cases of common respiratory illnesses. It is admitted, however, that these measures are only partially effective and, under conditions of active military training, can be properly applied only with considerable difficulty. It seemed desirable, therefore, to seek additional means of controlling this disease, particularly
KUHNS DM, NELSON CT, FELDMAN HA, KUHN LR. THE PROPHYLACTIC VALUE OF SULFADIAZINE: IN THE CONTROL OF MENINGOCOCCIC MENINGITIS. JAMA. 1943;123(6):335–339. doi:10.1001/jama.1943.02840410017006
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