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This report is concerned with acute pain and tenderness occurring in the right lower abdominal quadrant in 50 patients who did not have appendicitis. The admission diagnosis in all patients except 2 was acute appendicitis. This series of 50 patients were young men observed during a six month period at a station hospital. Among the early patients in the group 13 were operated on, and in each instance a normal appendix was removed. As more patients were seen and the findings pieced together the syndrome became more apparent and fewer patients were treated surgically. None of the latter patients exhibited any signs or sequelae of appendicitis in their subsequent course.
The abrupt onset was one of the salient features of this infection. Young men who had felt perfectly well at work, playing football, sitting in a classroom or taking a walk while off duty were suddenly seized with a
BUTSCH C, HARBERSON JC. ACUTE VIRUS INFECTION WITH NERVE ROOT INVOLVEMENT SIMULATING APPENDICITIS. JAMA. 1943;123(7):405–407. doi:10.1001/jama.1943.02840420017007
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