Neoplasms arising from nerve tissue in the posterior mediastinum are rather common. Not infrequently neurofibromas in this location are associated with other stigmas of neurofibromatosis (von Recklinghausen's disease). The present case is in this category but was unique because the intrathoracic neurofibromas were multiple and involved both the left vagus nerve and the thoracic sympathetic nerves. Two of the tumor masses arose from and were part of the left vagus nerve, and two neoplasms, entirely separate from the others, arose from the posterior-superior sympathetic chain. All the tumors were removed successfully and microscopic sections revealed that their histologic characteristics were identical. In order to remove the tumors involving the vagus, it was necessary to resect 15 cm. of the nerve and it is noteworthy that no deleterious effects were noted following the resection of the nerve itself.
REPORT OF CASE
A well developed white soldier aged 35 had no
Blades B, Dugan DJ. RESECTION OF THE LEFT VAGUS NERVE FOR MULTIPLE INTRATHORACIC NEUROFIBROMAS. JAMA. 1943;123(7):409–410. doi:10.1001/jama.1943.82840420002008b
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