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Comment & Response
August 1, 2017

Time to Diagnostic Testing After a Positive Colorectal Cancer Screening Test

Author Affiliations
  • 1Department of Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia
  • 2Division of Research, Kaiser Permanente Northern California, Oakland
JAMA. 2017;318(5):483. doi:10.1001/jama.2017.9312

To the Editor Prompt evaluation of abnormal findings is a central tenet of clinical care, but it is often unclear what “prompt” means in minimizing harms from delayed diagnosis in cancer screening. Is it days, weeks, or months? That is the lens through which to evaluate the biological and clinical implications of our recent study.1 We wish to clarify 2 points in the accompanying Editorial by Drs Rutter and Inadomi2: (1) the appropriate timing of colonoscopy and (2) potential methodological flaws that could bias the findings.

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