A dime-sized adhesive patch loaded with dissolving microneedles could one day be a cheaper, more practical alternative to the traditional flu shot. The microneedle patch features 100 tiny needles that release vaccine as they dissolve in the skin over the course of a few minutes. A team led by Mark R. Prausnitz, PhD, at the Georgia Tech School of Chemical and Biomolecular Engineering designed the patch.
In a phase 1 trial at Emory University using inactivated influenza vaccine formulated for the 2014-2015 flu season, the patch produced similar antibody responses as intramuscular injection at 28 days, and the immune responses were still present at 6 months. No serious adverse events were reported.
Abbasi J. Flu Vaccine Patch in Development. JAMA. 2017;318(6):510. doi:10.1001/jama.2017.9886
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