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JAMA Clinical Challenge
August 8, 2017

A Woman With Purple Macules on the Legs

Author Affiliations
  • 1The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York
JAMA. 2017;318(6):569-570. doi:10.1001/jama.2017.9227

A 30-year-old woman presented with widespread, erythematous, purpuric macules and papules on the abdomen and extremities. The eruption had been present for approximately 8 months and consisted of asymptomatic, self-resolving, and continuously appearing macules and papules. Her medical history was significant for chronic hepatitis B infection, for which tenofovir was initiated 4 months ago. Review of systems was positive only for occasional arthralgias in her knees and ankles. She was not taking any other medications.