It is not too unusual for a physician to have in his active years of practice a family with two or three generations of members with harelip, cleft palate or both. Recently we have observed a family in which through three generations there was a tendency to bilateral harelips and also hypertrophy of mucous cysts in the lower lip of each individual with harelip or cleft palate. We believe this unusual distribution of congenital deformities in one family to be of interest to the profession.
In this family of thirteen persons there were in three generations six persons with bilateral harelips. Some of these patients had an associated cleft palate, as might well be expected, but more interestingly each had a pair of hypertrophied mucous glands on the lower lip. These glands secrete a tenacious mucous material from two very prominent excretory ducts which open just above the mucocutaneous line
Straith CL, Patton HS. BILATERAL CONGENITAL MUCOUS CYSTS IN THREE GENERATIONS: THREE GENERATIONS OF MUCOUS CYSTS OCCURRING WITH HARELIP AND CLEFT PALATE. JAMA. 1943;123(11):693–694. doi:10.1001/jama.1943.82840460001007a
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