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Article
November 13, 1943

The Medical Use of Sulphonamides

JAMA. 1943;123(11):732. doi:10.1001/jama.1943.02840460066033

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Abstract

This booklet is a concise presentation of the present status of the sulfonamide compounds with a maximum of facts and a minimum of wasted words. The pages are crammed with information presented in a manner especially suitable for those who wish an accurate view of these agents without encountering confusing and frequently questionable details. The contents encompass an introduction and discussions on chemistry, pharmacology, general considerations governing the use of sulfonamides, questions of supply (in Great Britain), general scheme of dosage, regulation of dosage by the sulfonamide content of the patient's blood, treatment of specific infections, toxic reactions to sulfonamides, estimation of the concentration of sulfonamides in body fluids, bacteriologic studies and sterilization of sulfanilamide powder.

This memorandum has been prepared for the Therapeutic Requirements Committee (appointed by the Medical Research Council) by several well known authorities. Their attitude and conscientious approach to the subject is made evident by their

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