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November 20, 1943

The Role of Nutritional Deficiency in Nervous and Mental Disease

JAMA. 1943;123(12):797-798. doi:10.1001/jama.1943.02840470063030

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These sixteen papers by prominent laboratory and clinical investigators with a special interest in nutrition, the vitamins and the respiratory enzymes constitute a valuable, but not now complete, review of the role assumed by these factors in the metabolism of the nervous system as evinced especially by the neurologic manifestations of their deficiency. The book is divided into two parts, the first on contributions from the fundamental sciences, the second on clinical aspects. The ensuing discussions of the papers as they were read are also printed and constitute a valuable adjunct to the formal presentation of each subject.

In the section on contributions from the fundamental sciences Cowgill calls attention to some of the difficulties inherent in both animal and human nutritional studies, difficulties which have led some less restrained investigators into hasty publication of premature conclusions. Elvehjem reviews briefly some of the known and biochemically important interrelations between certain

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