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March 23, 1929

Die klinische Bedeutung der qualitativen Veränderungen der Leukozyten.

JAMA. 1929;92(12):1011-1012. doi:10.1001/jama.1929.02700380069047

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This is a report of a study, under the inspiration of Naegeli, of the changes in the polymorphonuclear leukocytes that occur in various infectious diseases. The author believes that Arneth's classification, because of its complexity, is not applicable to a study of the blood leukocytes. In this work he used the simpler classification of Schilling. Gloor shows that in various infectious diseases two main types of qualitative changes occur in the leukocytes. One of these is the appearance in the peripheral blood of young forms; that is, a shifting to the left according to Arneth's scheme. Gloor believes this a sign of the regenerative activity of the bone marrow. The other change in the leukocytes, and the one to which Gloor attributes more importance, is the presence of so-called pathologic or toxic changes, which he considers of a more degenerative nature. Included in them are basophilia of the protoplasm, toxic,

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