The many cutaneous manifestations of acquired sensitivity to the sulfonamide compounds have become well known with the widespread use of these drugs.1 The present case is reported because of the singular distribution of a dermatitis which broke out on two occasions following the use of sulfathiazole. In both instances it developed on areas of skin exposed to the sun and was limited to these. The case is also reported as an example of a severe reaction following administration of sulfathiazole by mouth ten days after it had been used topically in an ointment.
REPORT OF CASE
J. F., a technical sergeant aged 25, was admitted to an evacuation hospital June 24, 1942 because of a severe dermatitis on his hands, face and neck. Two and a half weeks before admission a few pustules appeared on the chin. A diagnosis of impetigo contagiosa was made, and sulfathiazole ointment was applied
Clark TW. DERMATITIS WITH UNUSUAL DISTRIBUTION FOLLOWING THE USE OF SULFATHIAZOLE. JAMA. 1943;123(15):958–959. doi:10.1001/jama.1943.82840500003007b
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