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Comment & Response
September 26, 2017

Long-term Intra-articular Steroid Injections and Knee Cartilage

Author Affiliations
  • 1Department of Orthopaedic Surgery, Stanford University, Redwood City, California
  • 2Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
  • 3St Luke’s Clinic—Orthopedics, Boise, Idaho
JAMA. 2017;318(12):1184-1185. doi:10.1001/jama.2017.11335

To the Editor The randomized clinical trial by Dr McAlindon and colleagues1 evaluated intra-articular administration of triamcinolone in the knee every 3 months. It is not surprising that clinical benefit 3 months following injection relative to placebo was not observed. The analgesic effect following corticosteroid injection is limited to weeks in duration.2

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