To the Editor The randomized clinical trial by Dr McAlindon and colleagues1 evaluated intra-articular administration of triamcinolone in the knee every 3 months. It is not surprising that clinical benefit 3 months following injection relative to placebo was not observed. The analgesic effect following corticosteroid injection is limited to weeks in duration.2
Maloney WJ, Jevsevar DS, Shea KG. Long-term Intra-articular Steroid Injections and Knee Cartilage. JAMA. 2017;318(12):1184–1185. doi:10.1001/jama.2017.11335
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