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Comment & Response
October 3, 2017

Effect of Different Iron Preparations for Young Children With Iron-Deficiency Anemia

Author Affiliations
  • 1Jikei University School of Medicine, Tokyo, Japan
JAMA. 2017;318(13):1282. doi:10.1001/jama.2017.11933

To the Editor In a randomized clinical trial comparing the efficacy of different iron drops containing the same amounts of essential iron for infants and young children (aged 9-48 months) with nutritional iron-deficiency anemia (IDA), ferrous sulfate drops increased mean hemoglobin concentration by 4.0 g/dL during the study period of 12 weeks compared with 3.4 g/dL with iron polysaccharide complex drops (difference, 1.0 g/dL; 95% CI, 0.4-1.6 g/dL).1 Consequently, Dr Powers and colleagues1 recommended ferrous sulfate as the first-line treatment for IDA among infants and young children.

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