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April 6, 1929

Thrombo-Angiitis Obliterans: Clinical, Physiologic and Pathologic Studies.

JAMA. 1929;92(14):1212. doi:10.1001/jama.1929.02700400070044

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Taking for their theme the disease thrombo-angiitis obliterans, also known as Buerger's disease, the authors have added many observations from their wide experience and have given a critical and comprehensive review on the subject. In the matter of pathology they agree in the main with Buerger's views except that they have been unable to find the acute inflammatory lesions in the deep vessels, illustrated in figure 84, page 334 (acute lesion in a large artery), of Buerger's book on Circulatory Disturbances. Since specific treatment of the cause of thrombo-angiitis obliterans is still unknown and since prophylaxis administered before the advent of the acute stage is also a closed book, much credit is due to these indefatigable workers for their studies on methods of enhancing the circulation. The treatment by nonspecific proteins is discussed at length in a manner sufficiently lucid to guide the practitioner, and "sympathetic neurectomy" is described with

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