Guillain-Barré syndrome (GBS) is an uncommon autoimmune disorder characterized by progressive weakness and diminished deep tendon reflexes following infection or, rarely, vaccination.1 Increased GBS incidence has been reported in countries affected by Zika virus,2 a flavivirus transmitted primarily by Aedes species mosquitoes.3 During the Zika virus epidemic in Puerto Rico, we conducted a case-control study to identify risk factors associated with GBS.
Dirlikov E, Medina NA, Major CG, Munoz-Jordan JL, Luciano CA, Rivera-Garcia B, Sharp TM. Acute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico. JAMA. 2017;318(15):1498–1500. doi:10.1001/jama.2017.11483