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Comment & Response
October 17, 2017

Acupuncture for Infertility in Polycystic Ovary Syndrome—Reply

Author Affiliations
  • 1Department of Obstetrics and Gynecology, Heilongjiang University of Chinese Medicine, Harbin, China
  • 2Department Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
  • 3Department of Biostatistics, Yale University School of Public Health, New Haven, Connecticut
JAMA. 2017;318(15):1502. doi:10.1001/jama.2017.13394

In Reply Ms Szmelskyj and Mr Szmelskyj question the rationale for increasing ovarian blood flow in women with PCOS, which conflicts with previous work.1 Electroacupuncture stimulation, independent of frequency, activates sympathetic nerve fibers innervating the ovaries during stimulation, an effect that is mediated via the central nervous system.2 The rationale for using low-frequency and not high-frequency electroacupuncture was because repeated low-frequency electroacupuncture treatment decreases sympathetic nerve activity and circulating testosterone and induces ovulation in women with PCOS.2

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