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Research Letter
October 24/31, 2017

Excretion of the Herbicide Glyphosate in Older Adults Between 1993 and 2016

Author Affiliations
  • 1Family Medicine and Public Health, University of California, San Diego, La Jolla
  • 2Health Research Institute Laboratories, Fairfield, Iowa
  • 3Radiology, University of California, San Diego, La Jolla
  • 4Family Medicine, Internal Medicine, and Public Health, University of California, San Diego, La Jolla
JAMA. 2017;318(16):1610-1611. doi:10.1001/jama.2017.11726

The herbicide Roundup is sprayed onto genetically modified crops and applied as a desiccant to most small non–genetically modified grains. Use of this herbicide has increased since 1994 when genetically modified crops were introduced in the United States. Glyphosate, the primary ingredient in the herbicide, is found in these crops at harvest.1 Environmental exposure through dietary intake of these crops has potential adverse health effects and can be assessed by measuring urinary excretion.24 We measured excretion levels of glyphosate and its metabolite aminomethylphosphonic acid (AMPA) in participants from the Rancho Bernardo Study (RBS) of Healthy Aging.

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