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Article
April 27, 1929

RADIOSENSITIVITY OF BONE

JAMA. 1929;92(17):1447. doi:10.1001/jama.1929.02700430049017
Abstract

Because of its hardness and strength, to which characteristics it owes its adaptation to the physiologic function it has to perform, and because of the length of time it can withstand decay and other destructive agencies, bone is commonly considered the most resistant tissue of the body. It is, however, only as properties of dead material that the hardness and strength and resistance of bone are apparent. As a living tissue, bone yields readily to constant pressure, even of softer tissues, by undergoing atrophy and resorption, and it may be quickly destroyed in inflammatory and neoplastic processes.

Resistance to radiation has also been ascribed to bone. Older tables of roentgen-ray dosages gave for bone a dose as much as eight times that for the skin of the face. With widespread use of the more deeply penetrating hard roentgen rays, bone has been found to be not immune to injury. Ewing

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