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JAMA Clinical Guidelines Synopsis
November 28, 2017

Diagnostic Testing for Obstructive Sleep Apnea in Adults

Author Affiliations
  • 1University of Chicago, Chicago, Illinois
JAMA. 2017;318(20):2035-2036. doi:10.1001/jama.2017.16722

Obstructive sleep apnea is characterized by recurrent episodes of complete (apnea) or partial (hypopnea) obstruction of the upper airway during sleep, causing snoring, intermittent hypoxemia and hypercapnia, cortical microarousals, increased oxidative stress, and sleep fragmentation.1 Nearly 30 million adults in the United States have OSA.2 Obstructive sleep apnea can lead to daytime sleepiness and impaired concentration, increased risk of motor vehicle collisions and occupational injuries, and reduced quality of life. The majority of cases of moderate to severe OSA remain undiagnosed.3