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Clinical Trials Update
November 28, 2017

Psychosocial Intervention Improves Adherence to Antidepressants

JAMA. 2017;318(20):1968. doi:10.1001/jama.2017.17955

A brief psychosocial intervention increased early antidepressant adherence among patients who were newly initiating treatment in a primary care setting, reported a study published in JAMA Psychiatry.

The trial randomly assigned 231 middle-aged and older patients (median age, 67.3 years) to the Treatment Initiation and Participation Program (TIP) or to usual care (treatment monitoring by primary care physicians). TIP helps patients address fears and perceived barriers to antidepressant use and develop a personal adherence strategy in three 30-minute sessions provided by social workers.

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