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Article
March 4, 1944

THE DIET AND CHRONIC PEPTIC ULCERITS RELATION TO THE COURSE OF THE DISORDER

JAMA. 1944;124(10):639-641. doi:10.1001/jama.1944.02850100029006
Abstract

In previous studies, lower levels of serum total protein, serum albumin and plasma ascorbic acid were found in patients with chronic peptic ulcer than in comparable persons without clinical evidence of gastrointestinal disorder.1 Since modification of the chemical structure of blood plasma influences the clinical course of ulcer through its action on motor and secretory functions of the stomach as well as by its effect on healing of the actual ulcer, it seemed of value to determine whether these changes in the blood were an integral part of the disease complex or reflected a deficiency in the diet.

This study presents an analysis of the dietary records of 16 of the group whose blood studies have been reported. These patients, while considered representative of the group as a whole, were selected primarily because of their willingness to cooperate. Their average age was 45, the youngest 21 and the oldest

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