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May 25, 1929


JAMA. 1929;92(21):1765. doi:10.1001/jama.1929.02700470041015

The frequent occurrence of sterility in the human species and the difficulties that its problems usually present to the physician who is expected to deal with them have contributed considerable interest to the more recent study of the subject in relation to diet. It has been only a few years since the announcement was made of the discovery of so-called vitamin E, which is believed to bear some relation to fertility in at least one animal species. It was found that, on certain diets, rats could grow to full maturity and appear normal but they were not able to reproduce. This type of sterility was soon identified as a dietary deficiency defect, as it can be prevented by a change in the food regimen. Specifically, this involved the addition of certain natural foods rich in the food factor designated as vitamin E, the antisterility vitamin. Concentrates of this potent principle