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June 1, 1929

La réserve alcaline.

JAMA. 1929;92(22):1885. doi:10.1001/jama.1929.02700480075031

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This monograph does not purport to be a summary of the entire question of the alkali reserve, but it is limited to certain problems with which the authors have been engaged. In their introduction the authors state the major premise of their work, which is that hydrochloric acid is neutralized in the circulation by direct combination with the proteins of the blood and especially with hemoglobin. Their theoretical treatment of the subject is therefore diametrically opposed to that of Henderson, Van Slyke and other modern workers, who have long since and on good grounds discarded this possibility. This study may be read by any one who wishes to pursue the matter further.

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